Dr. Oleg Alekseev

Associate Professor of Anatomy, School of Medicine

Associated Faculty, Doctor of Physical Therapy Program

MD, Kiev Medical University

PhD, Human Anatomy, Kiev Medical University

[email protected]



Academic Experience Summary
Dr. Alekseev has over 26 years of experience teaching in higher education. He has taught in the Ukraine and Japan, but has spent the past 13 years in North Carolina. His specialties include anatomy and cell and developmental biology.


  • PhD in Human Anatomy, Kiev Medical University, Kiev, Ukraine (1987)
  • MD, Kiev Medical University, Kiev, Ukraine (1984)

Professional Memberships

  • American Society for Cell Biology
  • Lineberger Comprehensive Cancer Center (University of North Carolina at Chapel Hill)

Research Interests

  • Prostate cancer diagnostics
  • Human reproductive system anatomy and physiology, clinical correlations
  • Clinical human anatomy

Peer-Reviewed Journal Publications (31)

  • Alekseev O.M, Richardson R.T., Tsuruta J.K., O'Rand M.G.: Depletion of the histone chaperone tNASP inhibits proliferation and induces apoptosis in prostate cancer PC-3 cells. Reproductive Biology and Endocrinology 9(1):50 (2011). PMID: 21496299.
  • Ali-Fehmi, R., Chatterjee, M., Ionan, A., Levin, N.K., Arabi, H., Bandyopadhyay, S., Shah, J.P., Bryant, C.S., Hewitt, S.M., O'Rand, M.G., Alekseev, O.M., Morris, R., Munkarah, A., Abrams, J., Tainsky, M.A. Analysis of the expression of human tumor antigens in ovarian cancer tissues. Cancer Biomarkers, Vol.6, N1, 33-48 (2010). PMID: 20164540.
  • Alekseev, O. M., Richardson, R. T., and O'Rand, M. G. Linker histones stimulate HSPA2 ATPase activity through NASP binding and inhibit CDC2/Cyclin B1 complex formation during meiosis in the mouse. Biology of Reproduction, Vol.81, N 4, 739-748 (2009).
  • Alekseev, O.M., Richardson, R.T., Alekseev, O., O'Rand, M.G. Analysis of gene expression profiles in HeLa cells in response to overexpression or siRNA-mediated depletion of NASP. Reproductive Biology and Endocrinology, 7: 45 (2009).
  • Richardson, R.T, Alekseev, O.M, Grossman, G., Widgren, E.E, Thresher, R., Wagner, E.J., Sullivan, K.D, Marzluff, W.F, O'Rand, M.G. Nuclear autoantigenic sperm protein (NASP), a  linker histone chaperone that is required for cell proliferation.  J. Biol. Chem., Vol. 281, N 28, 21526-21534 (2006).
  • Richardson, R.T., Alekseev, O., Alekseev, O.M. and O’Rand M.G. Characterization of the NASP promoter in 3T3 fibroblasts and mouse germ cells. Gene, Vol. 371, N1, 52-58 (2006).
  • Alekseev, O.M., Richardson, R.T., Pope M.R., and O'Rand, M.G. Mass spectrometry identification of NASP binding partners in HeLa cells. Proteins: Structure, Function, and Bioinformatics, Vol. 61, N1, 1-5 (2005).
  • Alekseev, O.M., Widgren, E.E., Richardson, R.T., and O’Rand, M.G. Association of NASP with HSP90 in mouse spermatogenic cells: stimulation of ATPase activity and transport of linker histones into nuclei. J. Biol. Chem., Vol. 280, N 4, 2904-2911 (2005).
  • Alekseev, O.M., Bencic, D.C., Richardson, R.T., Widgren, E.E., and O’Rand, M.G. Overexpression of the linker histone-binding protein tNASP affects progression through the cell cycle. J. Biol. Chem., Vol. 278, N 10, 8846-8852 (2003).
  • Alekseev O. Basal cells of the rat epididymal duct:  scanning electron microscopic study. AML, Vol.VI, N 1, 98-103 (2000).
  • Alekseev O. Principal epithelial cells of the human epididymis. Reports of Morphology, N 1, 1- 3 (2000).
  • Alekseev O. Intraepithelial lymphocytes of the rat epididymis. Reports of Vinnitsa State Medical University, N 1, 1-2 (2000).
  • Alekseev O. Veins of the human epididymis. Odessa Medical Journal, N 3, 47-49 (2000).
  • Alekseev O. Changes in the epididymis of men with obstructive infertility. Bukovinian Medical Herald, Vol. 4, N 2, 16-21 (2000).
  • Alekseev O. Changes in the rat epididymis after experimental obstruction of the vas deferens. Scientific bulletin of Uzhgorod University, medical series, N11, 3-6 (2000).
  • Alekseev O. Lymphatic bed of human epididymis. Likarska sprava, N 2, 53-56, (2000).
  • Alekseev O. Intersystemic arterial shunts in the region of the human epididymis. Urology, Vol. 4, N 1, 74-78 (2000).
  • Alekseev O. Fine structure of the rat epididymal contractile coat. Bukovinian Medical Herald, Vol. 3, N 4, 139-143 (1999).
  • Alekseev O. Blood supply of the human epididymis. Reports of Morphology, N 2, 150-151 (1999).
  • Alekseev O. Ultrastructural analysis of rat epididymis duct epithelium. Reports of Vinnitsa State  Medical University, N 2, 289-290 (1999).
  • Alekseev O. Epididymal hemomicrocirculatory bed in man. Likarska sprava, Vol. 6, 75-79 (1998).
  • Alekseev O. Structure of the epididymis in children. Scientific bulletin of the Uzhgorod University, Vol. 5, 11-13 (1998).
  • Alekseev O. Age peculiarities of the structure of the human epididymis. Scientific bulletin of the Uzhgorod University, Vol. 4, 191-194 (1997).
  • Alekseev O., Golovatsky A. Intraepithelial lymphocytes in the human epididymis. Scientific bulletin of the Uzhgorod University, Vol. 4, 194-196 (1996).
  • Alekseev O. Structure of the human epididymis. Scientific bulletin of the Uzhgorod  University, Vol. 2, 30-33 (1996).
  • Alekseev O.M. Embryogenesis of the human tongue. Arkh. Anat. Histol. Embriol. Vol.100,  N 6, 87-90 (1991).
  • Alekseev O. Hemomicrocirculatory bed of the rat epididymis. Morphology, 12, 102-105 (1990).
  • Alekseev O.M. The development of the human lingual tonsil in the prenatal period. Stomatologiia. Vol.5, 16-19 (1990).
  • Bobrik I.I., Alekseev O.M. Development of the microcirculatory bed of the human tongue in the prenatal period. Arkh. Anat. Histol. Embriol. Vol. 94, N1, 63-67 (1988).
  • Bobrik I.I., Alekseev O.M. Prenatal development of the human lingual glands. Vrach. Delo, Vol. 9, 89-91 (1988).
  • Bobrik I.I., Alekseev O.M. Electron-histochemical study of acetylcholinesterase activity in the endotheliocytes of human tongue microvessels in the prenatal period of morphogenesis. Vrach. Delo, Vol. 6, 88-90 (1987).

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